Monday, 22 February 2010

criminal experiment first to be run in Romania

First approval worldwide of fungicides with Initium® for wine and vegetables

2010-01-11 P-10-110
  • New fungicide products authorized by Romania in record time
  • Wine and vegetable growers profit from high efficacy and environmental compatibility

Limburgerhof , Germany – January 11, 2010 – Romania was the first country worldwide to authorize Initium ® products. Registration came at just the right moment, since wine growing in Romania is currently undergoing profound changes – Romanian winegrowers aim to establish themselves in the European market by improvements in quality. The innovative fungicide product will help the winegrowers to move over more quickly to profitable, high quality production.

In addition to the Initium product for grapes, which will be available in Romania from 2010 onwards under the name Enervin™, authorization was also granted for Zampro™, an Initium-based fungicide for the specialty crops potatoes, tomatoes, cucumbers and onions. Both products were extensively tested in field trials and showed high selectivity and efficacy against late blight and downy mildew. “Because of the very favourable environmental profile of Initium, the products were authorized in the record time of four years,” said Roland Ringel, Head of the Initium Global Development Project. And in fact, Initium products are not only in high degree environmentally compatible, they are also very user-friendly – they dissolve rapidly and dust-free in water, thus saving time and ensuring extra safety.

With the registration in Romania, BASF has reached an important milestone in its growth strategy for Central and Eastern Europe. Initium products will complement the portfolio alongside other modern compounds like the recently launched Cabrio ® Top, a multi disease fungicide for grapes. Next to Enervin™, Cabrio Top is expected to become a driving force in plant protection for grapes in Romania. As early as 2010 Romanian wine and vegetable growers can benefit from BASF’s comprehensive range of sustainable crop protection solutions. Forecasts indicate that Central and Eastern European countries such as Romania, Bulgaria, Russia and Ukraine will drive market growth in Europe during the next years. The crop protection market in Romania is expected to more than double over the period from 2007 to 2016. “Romanian farmers want to compete successfully on the European market. For this reason there is a great interest in innovative technologies”, said Michael Hess, Head of Central Europe Crop Protection. “Our highly effective and environmentally compatible crop protection products will enable winegrowers and farmers to produce high yields and healthy crops with only minimum residue levels in accordance with EU regulations.” Initium products are expected to be registered in the Netherlands and Great Britain in the first half of 2010. Other European countries will follow.

About the Crop Protection division

With sales of €3.4 billion in 2008, BASF’s Crop Protection division is a leader in crop protection and a strong partner to the farming industry providing well-established and innovative fungicides, insecticides and herbicides. Farmers use these products and services to improve crop yields and crop quality. Other uses include public health, structural/urban pest control, turf and ornamental plants, vegetation management, and forestry. BASF aims to turn knowledge rapidly into market success. The vision of BASF’s Crop Protection division is to be the world’s leading innovator, optimizing agricultural production, improving nutrition, and thus enhancing the quality of life for a growing world population. Further information can be found on the web at www. agro.basf.com .

About BASF

BASF is the world’s leading chemical company: The Chemical Company. Its portfolio ranges from chemicals, plastics and performance products to agricultural products, fine chemicals and oil and gas. As a reliable partner BASF helps its customers in virtually all industries to be more successful. With its high-value products and intelligent solutions, BASF plays an important role in finding answers to global challenges such as climate protection, energy efficiency, nutrition and mobility. BASF posted sales of more than €62 billion in 2008 and had approximately 97,000 employees as of the end of the year. Further information on BASF is available on the Internet at www.basf.com.



Source: http://www.basf.com/group/pressrelease/P-10-110


ametoctradin

Fr: amétoctradine; Ru: аметоктрадин


Status: ISO 1750 (provisionally approved)
IUPAC: 5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS: 5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Reg. No.: 865318-97-4
Formula: C15H25N5
Activity: fungicides (triazolopyrimidine fungicides)
Notes:
Structure: Structural formula of ametoctradin
Pronunciation: ǎ-mě-tǒk-tra-dǐn
Guide to British pronunciation
InChI: InChI=1/C15H25N5/c1-3-5-6-7-8-9-10-12-13(4-2)19-15-17-11-18-20(15)14(12)16/h11H,3-10,16H2,1-2H3





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Ametoctradin - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information

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Chemical ID
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Water
Water quality standards and physical properties affecting water contamination potential.
Ecotoxicity
Toxicity to aquatic organisms.
Related Chems
List of chemicals in the same family, including breakdown products, salts, esters, isomers, and other derivatives.

Chemical Identification and Use for Ametoctradin

Basic Identification Information About This Chemical
Chemical Name: Ametoctradin
CAS Number:
U.S. EPA PC Code:
CA DPR Chem Code:
Molecular Weight: 0
Use Type: Fungicide
Chem Class: Triazolopyrimidine
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Additional Resources About This Chemical Class and Use Type

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Current and historic U.S. registered products
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Signs and Symptoms of Ametoctradin Poisoning


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If you have a poisoning emergency in the United States call 1-800-222-1222.
If the victim has collapsed or is unconscious, call 911.
Sorry! No symptoms for this chemical or chemical group are available. See related chemicals for possible additional information.


Toxicity Information for Ametoctradin


Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. Why?
Summary Toxicity Information
PAN Bad Actor
Chemical 1 Acute
Toxicity 2 Carcinogen Cholinesterase
Inhibitor Ground
Water Contaminant Developmental or
Reproductive Toxin Endocrine
Disruptor
Not Listed

No



Indicates high toxicity in the given toxicological category. Indicates no available weight-of-the-evidence summary assessment. For additional information on toxicity from scientific journals or registration documents, see the "Additional Resources for Toxicity " section of the chemical detail page.
1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.
Additional Resources about the Toxicity of this Chemical

See the Global Pesticide Resources page for many additional links.
Detailed Toxicity Information


Acute Toxicity 2
Ametoctradin
WHO Acute Hazard
TRI Acute Hazard
Material Safety Data Sheets
Acute rating from U.S. EPA product label
U.S. NTP Acute Toxicity Studies
View Studies
Cholinesterase Inhibitor Not Listed
Not Listed
Not Available
No Consensus Value
No NTP Studies

No
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

Cancer Information
Ametoctradin
IARC Carcinogens
U.S. NTP Carcinogens
California Prop 65 Known Carcinogens
U.S. EPA Carcinogens
TRI Carcinogen Not Listed
Not Listed
Not Listed
Not Listed
Not Listed

Endocrine Disruption
Ametoctradin
Illinois EPA list
Keith list
Colborn list
Benbrook list
Danish Inert list
EU list Not Listed
Not Listed
Not Listed
Not Listed
Not Listed
Not Listed

Reproductive and Developmental Toxicity
Ametoctradin
CA Prop 65 Developmental Toxin
U.S. TRI Developmental Toxin
CA Prop 65 Female Reproductive Toxin
CA Prop 65 Male Reproductive Toxin
U.S. TRI Reproductive Toxin Not Listed
Not Listed
Not Listed
Not Listed
Not Listed

Chemicals of Special Concern
Ametoctradin
PAN Bad Actors
PAN Dirty Dozen list Not Listed
Not Listed

Water Pollution Potential and Criteria for Ametoctradin

Water Pollution Potential


PAN Ground Water Contaminant Rating Insufficient Data


Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.

Regulatory Information for Ametoctradin

International Regulatory Status


Registration in Selected Countries Registration in Selected Countries:
Ametoctradin


UNEP Persistent Organic Pollutant (POP)
UNEP Prior Informed Consent Chemical (PIC)
WHO Obsolete Pesticide Not Listed
Not Listed
Not Listed

U.S. and California Regulatory Status
U.S. EPA Registered
U.S. EPA Hazardous Air Pollutant
U.S. EPA Minimum Risk Pesticide (25b list)

CA Registered
CA Groundwater Contaminant
CA Toxic Air Contaminant No
Not Listed
No

No
Not Listed
Not Listed

Maximum Tolerance and Residue Levels
Codex Alimentarius
(UN FAO Maximum Residue Limits)
U.S. Maximum Tolerance Levels
European Union Maximum Residue Levels Go to web site

Go to web site
Go to web site

Ecotoxicity for Ametoctradin


Note! Information for many chemicals is incomplete and may not be fully representative of effects on the environment. Why? Click on underlined terms for definitions and additional information.
Aquatic Ecotoxicity
All Toxic Effects for Organism Group
Organism Group Effects Noted

Sorry, no ecotoxicity data available for this chemical. Try related chemicals.

Summary of Acute Toxicity for Organism Group

Sorry, no acute ecotoxicity data available for this chemical. Try related chemicals.

Terrestrial Ecotoxicity

We are seeking funding to incorporate terrestrial ecotoxicity data analogous to the aquatic ecotoxicity data in the space above. Watch this space!

Related Chemicals for Ametoctradin

CAS Number Relation Reason Chemical Name Chem Detail Registration Symptoms California Use Chem Use Type U.S. EPA Reg PAN Bad Actor
Parent P Ametoctradin View View View View Fungicide No Not Listed

Working with the Information on this Page

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* Data marked with an asterisk indicates that this chemical is not explicitly listed on the corresponding list. Instead, it belongs to a group of chemicals that IS designated on the list. For example, if an agency assigns a classification of reproductive toxicant to "mercury compounds", that classification is applied to all mercury compounds in the PAN Pesticide database, which are then marked with an asterisk.

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Citation: Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (San Francisco, CA, 2009), http:www.pesticideinfo.org.
© 2000-2009 Pesticide Action Network, North America. All rights reserved.



ametoctradin
** Initium ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION

Description: Novel fungicide for the control of late blight and downey mildew on potatoes and other crops

Introduction: 2009, Germany

EC Directive 91/414:
Status DAR
Dossier rapporteur/co-rapporteur -
Date inclusion expires -

Approved for use () or known to be used () in the following European countries:

AT


BE


BG


CY


CZ


DE


DK


EE


ES


FI


FR


GR


HU


IE


IT


LT


LU


LV


MT


NL


PL


PT


RO


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SK


UK





















































Also registered in: Registration expected by 2010-2011

General status:
Pesticide Type Fungicide
Chemical Group Pyrimidylamine
Mode of Action Selective
CAS RN 865318-97-4
EC Number -
CIPAC Number 818
US EPA Chemical code -
Chemical Formula C15H25N5
SMILES n1c(c(c(n2ncnc12)N)CCCCCCCC)CC
International Chemical Identifier (InChI) InChI=1/C15H25N5/c1-3-5-6-7-8-9-10-12-13(4-2)19-15-17-11-18-20(15)14(12)16/h11H,3-10,16H2,1-2H3
Structure diagram available? Yes
Molecular Mass (g mol-1) 275.39
IUPAC Name 5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS Name 5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Other status information -
Herbicide Resistance (HRAC) Classification Not applicable
Insecticide Resistance (IRAC) Classification Not applicable
Fungicide Resistance (FRAC) Classification Not known
Physical State -

Formulations:
Property Value
Example manufacturers of products using this active

* BASF

Example products using this active -
Associated substances -
UK LERAP status No UK approval for use
Formulation and application details -


ENVIRONMENTAL FATE

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) - - -
Solubility - In organic solvents at 20oC (mg l-1) - - -
Melting Point (oC) - - -
Boiling Point (oC) - - -
Degradation point (oC) - - -
Flashpoint (oC) - - -
Octanol-water partition coefficient at pH 7, 20oC P: - - -
Log P: - - -
Bulk density (g ml-1)/Specific gravity - - -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) - - -
Henry's law constant at 25oC (Pa m3 mol-1) - - -
Henry's law constant at 20oC (dimensionless) - - -
Soil degradation (days) (aerobic) DT50 (typical): - - -
DT50 (lab at 20oC): - - -
DT50 (field): - - -
DT90 (lab at 20oC): - - -
DT90 (field): - - -
Note: -
Aqueous photolysis DT50 (days) at pH 7 Value: - - -
Note: -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value: - - -
Note: -
Water-Sediment DT50 (days) - - -
Water phase only DT50 (days) - - -
GUS leaching potential index - - -
SCI-GROW groundwater index (µg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value: - - -
Note: -
Potential for particle bound transport index - - -
Koc - Organic-carbon sorption constant (ml g-1) - - -
pH sensitivity:
Note:
Freundlich isotherm Kf: - - -
1/n: - -
Note: -
Maximum UV-vis absorption L mol-1 cm-1 - - -


ECOTOXICOLOGY

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF: - - -
CT50 (days): - -
Bioaccumulation potential - - -
Mammals - Acute oral LD50 (mg kg-1) - - -
Mammals - Short term dietary NOEL (mg kg-1): - - -
(ppm diet): - -
Birds - Acute LD50 (mg kg-1) - - -
Fish - Acute 96 hour LC50 (mg l-1) - - -
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) - - -
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) - - -
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (µg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1: - - -
% Effect: - - -
Other arthropod (2) LR50 g ha-1: - - -
% Effect: - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1: - - -
NOEAEC mg l-1: - - -


HUMAN HEALTH

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) - - -
Mammals - Dermal LD50 (mg kg-1 body weight) - - -
Mammals - Inhalation LC50 (mg l-1) - - -
WHO Classification NL - Not listed
US EPA Classification (formulation) - - -
EC Risk Classification -
EC Safety Classification -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) - - -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 - - -
Exposure Limits - - -
Exposure Routes Public: -
Occupational: -
Examples of European MRLs (mg kg-1) Value: -
Note: For the EU pesticides database click here
Drinking Water MAC (µg l-1) - - -

Health issues:
Carcinogen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-


-


-




-


-


-


-
General human health issues [No information available]
Handling issues [No information available]

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data


TRANSLATIONS

Language Name
English ametoctradin
French -
German -
Danish -
Italian -
Spanish -
Greek -
Slovenian -
Polish -
Swedish -
Hungarian -
Dutch -
Site last updated: Monday 22 February 2010
Contact: aeru@herts.ac.uk
Acknowledgements: The PPDB website has been compiled from the EMA/EMA On-line pesticide properties database, with additional input from the EU-funded FOOTPRINT project and others. Special thanks are due to Don Wauchope, Nick Jarvis (SLU Sweden), Stefan Reichenberger (University of Giessen, Germany) and Benoit Réal (ARVALIS-Institut du Végétal, France) for their assistance in sourcing additional data. The funding of FOOTPRINT by the European Commission as part of its Framework Programme for Research and Development is also gratefully acknowledged.


3 comments:

Andrei S. said...

Mda... asta e trist. E foarte trist. "Parcă" face parte dintr-un plan mai mare de exterminare în masa a popoarelor, începând cu poporul nostru. Ca şi cum nu ar fi suferit destul de-a lungul veacurilor.

Adevărul este că mă bucur, sincer. În ritmul curent al lucrurilor românul de rând nu s-ar fi trezit din lunga şi dureroasa somnolenţă. Nu pot decât să sper că următoarele cuvinte vor avea puterea de a se adeveri...

"Numai atunci când omul va sta faţă în faţă cu propria sa distrugere va realiza adevărul tuturor lucrurilor. Şi chiar dacă va fi prea târziu, măcar îşi va salva umanitatea..."

Viaţa va fi din ce în ce mai grea în ţărişoara noastră. Singura şansă pe care o avem, ca popor, este să ne TREZIM.

Închei cu vorbele lui Eminescu:

"Panule, ştii tu că în lumea asta nu este nimic mai interesant decât istoria poporului nostru, trecutul lui... Tot, tot este un şir neîntrerupt de martiri."

Numai bine.

Custos said...

Deci problemele cu articol:
Ai copiat 2 articole unu dupa celalat, fara link la doilea sa verificam sursa informatiilor.

1. PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. NOTE! Because there are no authoritative lists of Endocrine Disrupting (ED) chemicals, EDs are not yet considered PAN Bad Actor chemicals.
2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products


Ai postat ceva informatii despre un pesticid ca e toxic(socant) sau carcinogen sau... este o lista de posibilitati. Ce effect are precis?

Nu ai date despre ce efect are asupra plantelor sau asupra mancari.

Produsul e folosit din 2009 in germania. Nu ai date despre schimbari legat de sanatate de adunci in zona afectata.

In scurt: show me your data!

Anonymous said...

http://sitem.herts.ac.uk/aeru/iupac/Reports/1648.htm
- mitochondrial respiration inhibitor by interferring with complex III (cancerigen)